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Evaluation of BacT/Alert FA Blood Culture Bottles and T2Candida Assay for Detection of Candida in the Presence of Antifungals

The poster presented at ASM Microbe (2016) in Boston, MA, presented by investigators from the University of Houston College of Pharmacy, suggests that T2Candida Panel performance is not impacted by antifungals and can be a reliable method for detecting patients with candidemia. Key findings include the following:

  • The presence of antifungals fluconazole (FLU) and caspofungin (CAS) did not impact the performance of the T2Candida Panel
  • FLU reduced the detection rate of Candida in blood culture bottles, and both FLU and CAS prolonged time to positivity in blood culture bottles (34.6 ± 16.3 hrs versus 5.3 ± 0.8 hrs for the T2Candida Panel)